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Yuko ISOBE
Researchmap
Assistant Professor (Research fellowship-RPD)Institute for Advanced Academic Research / Graduate School of Medicine
Keywords
Mental Disorders、Psychotherapy、Children and Adolescents、Neuroimaging Analysis、Biological Biomarkers
Professional Memberships
Japanese Physical Therapy Association、Japanese Society of Anxiety and Related Disorders、The Japanese Association of Cardiac Rehabilitation、Japanese Society for Brain Function and Rehabilitation
Research Theme
Elucidating the Neural Mechanisms of Mental Disorders in Children and Adolescents through Neuroimaging
Abstract
Mental disorders commonly emerge during childhood and adolescence and pose a significant risk of leading to social issues such as school refusal and social withdrawal. Therefore, early and appropriate therapeutic interventions are crucial. Treatment approaches include psychotherapy, pharmacotherapy, and environmental adjustments; however, there is considerable individual variability, and no single treatment is universally effective. Hence, there is an urgent need to establish evidence-based, personalized treatment strategies.
Recent research has enhanced our understanding of the pathophysiology of mental disorders and the mechanisms underlying treatment efficacy. However, biological biomarkers that could serve as clinical guidelines have not yet been well established. Additionally, the clinical and pathophysiological diversity of mental disorders makes it challenging to rely on a single biomarker for diagnosis and treatment.
To refine treatment strategies for mental disorders, we aim to develop a highly accurate predictive model for symptom improvement by integrating biological and psychological factors. By elucidating the relationship between brain imaging data and behavioral and psychological states, we hope to contribute to the advancement of digital mental healthcare technologies. Through this research, we strive to create an environment where more children can receive appropriate support.