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Wataru KUDO
Researchmap
Assistant ProfessorInstitute for Advanced Academic Research / Graduate School of Medicine
Keywords
Epigenetics, Childhood cancer, Next generation sequencers, Multiomics
Professional Memberships
The Japanese Society of Pediatric Surgeons, The Japan Surgical Society, The Japanese Cancer Association, The Japanese Society of Pediatric Hematology/Oncology, The Japanese Society for Epigenetics, The Japanese Society for Gastroenterological Carcinogenesis
Research Theme
Development of novel medical strategies for childhood cancer by multiomics analysis
Abstract
"Childhood cancer" refers to malignant tumors that occur in children. In Japan, approximately 2,000-2,500 new cases are diagnosed annually. Advances in diagnosis and treatment have led to improved prognosis. However, challenges persist, such as cases where standard treatment fails to succeed, or where complications arising from aggressive therapies negatively impact the development of children even after overcoming cancer.
My research aims to establish novel medical strategies to improve prognosis and enhance the quality of life after treatment for cancer. I primarily focus on hepatoblastoma, utilizing comprehensive approaches, including genome-wide analysis of gene expression, DNA methylation, and histone modification to investigate factors contributing to the development and progression of hepatoblastoma. Expanding upon these studies, I integrate clinical imaging and nutritional analyses to advance toward establishing novel medical strategies for overcoming childhood cancer.