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Takuya NAKAGAWA
Researchmap
LecturerChiba University Institute for Advanced Academic Research / Graduate School of Medicine
Keywords
Epigenome, Extrachromosomal DNA (ecDNA), HPV, Single cell sequencing, and Head and neck cancer
Professional Memberships
Japanese Cancer Association, Japanese Society of Otorhinolaryngology Head and Neck Surgery, Japan Society for Head and Cancer, Japan Society for Head and Neck Surgery, American Association for Cancer Research
Research Theme
New Medical Strategy for Virus-associated Cancer via Multi-omics Analysis Focusing on Extrachromosomal DNA.
Abstract
Extrachromosomal DNA (ecDNA) is extensively implicated in carcinogenesis through a variety of potential carcinogenic mechanisms. Recently, my research team succeeded in identifying a human-viral hybrid ecDNA (hybrid ecDNA), a fusion of the human genome and viral genome, in Virus-associated oropharyngeal cancer.
Currently, my research is focused on this structure with the aim of developing innovative medical strategies in Virus-associated cancer.